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Influenza virus non-structural protein NS1: interferon antagonism and beyond

3 Sept 2014

Abstract excerpt

Most viruses express one or several proteins that counter the antiviral defences of the host cell. This is the task of non-structural protein NS1 in influenza viruses. Absent in the viral particle, but highly expressed in the infected cell, NS1 dramatically inhibits cellular gene expression and prevents the activation of key players in the IFN system. In addition, NS1 selectively enhances the translation of viral...

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PMID: 25182164
DOI: 10.1099/vir.0.069542-0

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