Article

Assembloid model to study loop circuits of the human nervous system

2024-10-14

Abstract excerpt

Neural circuits connecting the cerebral cortex, the basal ganglia and the thalamus are fundamental networks for sensorimotor processing and their dysfunction has been consistently implicated in neuropsychiatric disorders 1-9 . These recursive, loop circuits have been investigated in animal models and by clinical neuroimaging, however, direct functional access to developing human neurons forming these networks has...

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Literature Corpus work: 965af401-f701-53ab-8c5c-3cda47911143
DOI: 10.1101/2024.10.13.617729

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