Article

Improved estimation of phenotypic correlations using summary association statistics

2020-12-11

Abstract excerpt

Estimating the phenotypic correlations between complex traits and diseases based on their genome-wide association summary statistics has been a useful technique in genetic epidemiology and statistical genetics inference. Two state-of-the-art strategies, Z-score correlation across null-effect SNPs and LD score regression intercept, were widely applied to estimate phenotypic correlations. Here, we propose an improve...

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Literature Corpus work: 964dcb1d-46e5-5530-93c8-22e4c36cfe14
DOI: 10.1101/2020.12.10.419325

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