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Article

Cross-Phenotype Association Analysis Using Summary Statistics from GWAS.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Li Xiaoyin, Zhu Xiaofeng

Abstract excerpt

For over a decade, genome-wide association studies (GWAS) have been a major tool for detecting genetic variants underlying complex traits. Recent studies have demonstrated that the same variant or gene can be associated with multiple traits, and such associations are termed cross-phenotype (CP) associations. CP association analysis can improve statistical power by searching for variants that contribute to...

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PMID: 28980259
DOI: 10.1007/978-1-4939-7274-6_22
PMCID: PMC6417431

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