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Donor tissue-resident memory-like T and NK cells generate a transient peripheral chimerism in lung transplant recipients, potentially protective from chronic lung allograft dysfunction

2023-06-19

Abstract excerpt

Lung transplantation (LTx) is the only definite treatment option of patients suffering from end- stage lung disease. Long-term outcome is hampered by chronic allograft dysfunction resulting from poorly defined immune mechanisms. In this study of 97 lung recipients, we demonstrate dynamic changes of T, B and NK cell subsets early after lung transplantation with a selective decrease in memory CD4 + and CD8 + T cel...

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Literature Corpus work
964aafc1-fc02-5f3c-a69c-3a3c7e18e6d1
DOI
10.1101/2023.06.16.543190
Open publication

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Donor tissue-resident memory-like T and NK cells generate a transient peripheral chimerism in lung transplant recipients, potentially protective from chronic lung allograft dysfunctionDOI 10.1101/2023.06.16.543190
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