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Article

Pharmacogenetic Study of Anti-TB Drugs in the Native Ancestry Peruvian Population.

Pharmacology research & perspectives - 1 Jun 2025

Jaramillo-Valverde Luis, Horton Mary K, Poterico Julio A, Lanata Cristina M, Guio Heinner

Abstract excerpt

In Peru, 33 113 individuals were diagnosed with tuberculosis (TB) in 2023. While TB treatments are generally effective, 3.4% to 13% of cases are associated with significant adverse drug reactions, with drug-induced liver injury (DILI) being the most prevalent. Limited data exist on genetic risk factors for DILI in Latin America; even less is known about these factors in native Peruvian populations. This study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40517315
DOI: 10.1002/prp2.70135
PMCID: PMC12167507

Genes

AGBL4
GSTP1
SLCO1B1
CYP2B6
NAT2
PGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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