Article

Structural basis of fitness of emerging SARS-COV-2 variants and considerations for screening, testing and surveillance strategy to contain their threat

2021-01-31

Abstract excerpt

While emergence of new SAS-COV-2 variants is posing grave challenge to efforts to deal with the COVID-19 pandemic, the structural and molecular basis of their fitness remain poorly understood. We performed in silico analysis of structures of two most frequent SARS-COV-2 mutations, namely, N501Y and E484K, to identify plausible basis of their fitness over the original strain. The analysis suggested that the N501Y m...

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Literature Corpus work: 9613a85c-0a18-56a1-a38c-40b80a7e58db
DOI: 10.1101/2021.01.28.21250666

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