Article
Higher infectivity of the SARS-CoV-2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data.
Journal of cellular physiology - 1 Oct 2021
Khan Abbas, Zia Tauqir, Suleman Muhammad, Khan Taimoor, Ali Syed Shujait, Abbasi Aamir Ali, Mohammad Anwar, Wei Dong-Qing
Abstract excerpt
The evolution of the SARS-CoV-2 new variants reported to be 70% more contagious than the earlier one is now spreading fast worldwide. There is an instant need to discover how the new variants interact with the host receptor (ACE2). Among the reported mutations in the Spike glycoprotein of the new variants, three are specific to the receptor-binding domain (RBD) and required insightful scrutiny for new therapeutic...
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