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SARS-CoV-2 Mutations and Their Impact on Diagnostics, Therapeutics and Vaccines

22 Feb 2022

Abstract excerpt

With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2 variants was inevitable. Several mutations have been identified in the SARS-CoV-2 genome, with the spike protein as one of the mutational hot spots. Specific amino acid substitutions such as D614G and N501Y were found to alter the transmissibility and virulence of the virus. The WHO has classified the variants identified with...

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PMID: 35273977
DOI: 10.3389/fmed.2022.815389

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