Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional alterations caused by mutations reflect evolutionary trends of SARS-CoV-2.

Briefings in bioinformatics - 22 Mar 2021

Cheng Liang, Han Xudong, Zhu Zijun, Qi Changlu, Wang Ping, Zhang Xue

Abstract excerpt

Since the first report of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the COVID-19 pandemic has spread rapidly worldwide. Due to the limited virus strains, few key mutations that would be very important with the evolutionary trends of virus genome were observed in early studies. Here, we downloaded 1809 sequence data of SARS-CoV-2 strains from GISAID before April 2020 to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to COVID-19
Share to Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Open Reading Frames

Share to SARS-CoV-2

Share to SARS-CoV-2 and COVID-19 Research

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 33580783
DOI: 10.1093/bib/bbab042
PMCID: PMC7953981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional alterations caused by mutations reflect evolutionary trends of SARS-CoV-2.PMID 33580783Read ↗

Genome-wide analysis of SARS-CoV-2 virus strains circulating worldwide implicates heterogeneitySemantic proximity Read ↗

Emerging mutations in spike and other structural proteins of SARS-CoV-2Semantic proximity Read ↗

Mutations in SARS-CoV-2; Consequences in structure, function, and pathogenicity of the virus.Semantic proximity Read ↗

Mutations in SARS-CoV-2 structural proteins: a global analysis.Semantic proximity Read ↗

Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage.Semantic proximity Read ↗

Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of RBD mutant with lower ACE2 binding affinitySemantic proximity Read ↗

SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021.Semantic proximity Read ↗

Meta-Analysis and Structural Dynamics of the Emergence of Genetic Variants of SARS-CoV-2Semantic proximity Read ↗

The Development of SARS-CoV-2 Variants: The Gene Makes the DiseaseSemantic proximity Read ↗

Genome-Wide Identification and Characterization of Point Mutations in the SARS-CoV-2 GenomeSemantic proximity Read ↗

Large-scale population analysis of SARS-CoV-2 whole genome sequences reveals host-mediated viral evolution with emergence of mutations in the viral Spike protein associated with elevated mortality ratesSemantic proximity Read ↗

SARS-CoV-2 outbreak: role of viral proteins and genomic diversity in virus infection and COVID-19 progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.