Article

Chemovaccination with a novel antimalarial targeting the late liver stage induces durable immunity against malaria

2025-07-22

Abstract excerpt

<h4>Summary</h4> Vaccination with Plasmodium falciparum , the most lethal malaria parasite, using sporozoites that arrest during liver stage infection either by irradiation, genetic attenuation or chemotherapy have been developed, with late liver stage arrest providing very high efficacy. Such vaccines require complex manufacture, deployment and intravenous administration. Here, we report an alternative strategy...

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Literature Corpus work: 96073645-7e52-57a9-947d-7e289928bdf5
DOI: 10.1101/2025.07.22.666032

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