Article
Genome-wide translating mRNA analysis following ketamine reveals novel targets for antidepressant treatment
2018-01-31
Abstract excerpt
Low-dose ketamine is an efficacious antidepressant for treatment-resistant unipolar and bipolar depressed patients. Major Depression Disorder patients receiving a single infusion report elevated mood within two hours, and ketamine’s antidepressant effects have been observed as long as seven days post-treatment. In light of this remarkable observation, efforts have been undertaken to “reverse-translate” ketamine’s...
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Identifiers and source
- Literature Corpus work
- 95f1be83-ffd1-5a61-9a02-5257eef73640
- DOI
- 10.1101/254904