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Article

Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress

2023-05-05

Abstract excerpt

The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap between animal models and clinical endpoints. Here, we hypothesize that comparative analysis of molecular data from different experimental systems of chronic stress an...

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Literature Corpus work
e1fbe57f-e5ec-5030-86cf-3e63470c238c
DOI
10.1101/2023.05.04.539419
Open publication

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Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stressDOI 10.1101/2023.05.04.539419
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