Article

Reversing DNA methylation by heterokaryon-mediated reprogramming

2013-01-01

Abstract excerpt

Genomic imprinting directs the allele‐specific expression of a subset of loci according to their parental origin. Monoallelic expression of these genes is regulated by imprinting control regions (ICRs) and is established in the embryonic germ line through differential DNA methylation. Differentiated cells can be reprogrammed to pluripotency by several strategies including the ectopic expression of specific ‘induce...

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Literature Corpus work: 95e3ed0a-52b4-5e06-9246-0234d466ff60
DOI: 10.25560/14505

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