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Biobank-scale characterization of Alzheimer’s disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestries

2024-11-04

Abstract excerpt

Alzheimer’s disease and related dementias (AD/ADRDs) pose a significant global public health challenge, underscored by the intricate interplay of genetic and environmental factors that differ across ancestries. To effectively implement equitable, personalized therapeutic interventions on a global scale, it is essential to identify disease-causing mutations and genetic risk and resilience factors across diverse anc...

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Literature Corpus work
95d975bb-e72a-5f0e-ac3e-f4944ed0ce00
DOI
10.1101/2024.11.03.24313587
Open publication

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Biobank-scale characterization of Alzheimer’s disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestriesDOI 10.1101/2024.11.03.24313587
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