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Article

Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2025

Willett Julian Daniel Sunday, Waqas Mohammad, Choi Younjung, Ngai Tiffany, Mullin Kristina, Tanzi Rudolph E, Prokopenko Dmitry

Abstract excerpt

INTRODUCTION: Alzheimer's disease (AD) is the most prevalent form of dementia. While many AD-associated genetic determinants have been identified, few studies have analyzed individuals of non-European ancestry. METHODS: We conducted a multi-ancestry genome-wide association study (GWAS) of clinically diagnosed AD and AD-by-proxy using whole genome sequencing data from the National Institute on Aging Genetics of...

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Source

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Identifiers

PMID: 39998322
DOI: 10.1002/alz.14592
PMCID: PMC11852348

Genes

CDO1
DYM
FBN2
KCNG1
LASP1
LMX1A
MOB1A
MORC1
NEO1
PDE4D
RPL23
SLC35G3
TIAM1
VWA5B1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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