Article

Consensus meta-analysis of genome-wide association studies for Alzheimer’s disease and related dementia

2025-10-23

Abstract excerpt

To better characterize the genetic architecture underlying Alzheimer’s disease (AD) and related dementia (ADRD), we performed a meta-analysis of European ancestry genome-wide association studies in 128,681 cases or proxy cases of ADRD and 849,833 (proxy) controls. We identified 91 genetic loci associated with ADRD risk, including 16 which are novel, and 56 which are specifically detected in clinically diagnosed AD...

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Literature Corpus work: e5bad4c0-ccff-5334-b705-acbebd7c303e
DOI: 10.1101/2025.10.20.25338060

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