Article
Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease.
Current Alzheimer research - 1 Jan 2018
Qian Winnie, Fischer Corinne E, Schweizer Tom A, Munoz David G
Abstract excerpt
BACKGROUND: Psychosis is a common phenomenon in Alzheimer's disease (AD). The APOE ε4 allele is the strongest genetic risk factor for the development of AD, but its association with psychosis remains unclear. OBJECTIVE: We investigated the associations between psychosis, subdivided into delusions and hallucinations, as well as APOE ε4 allele on cognitive and functional outcomes. Secondarily, we investigated the...
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