Article

NCX1/Ca2+ promotes autophagy and decreases bortezomib activity in multiple myeloma through non-canonical NFκB signaling pathway

2024-01-02

Abstract excerpt

<title>Abstract</title> Although bortezomib (BTZ) is the cornerstone of anti-multiple myeloma (MM) therapy, the inevitable primary and secondary drug resistance still seriously affects the prognosis of patients. New treatment strategies are in need. Sodium-calcium exchanger 1 (NCX1) is a calcium-permeable ion transporter on the membrane, and our previous studies showed that low NCX1 confers inferior viability...

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Literature Corpus work: 9580f883-6745-5c65-9f7f-bbe4fc9bbe0f
DOI: 10.21203/rs.3.rs-3776793/v1

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