Article

Discovery of Cytotoxic Truncated Vitamin D Derivatives Against Both Bortezomib‐Sensitive and Resistant Multiple Myeloma Phenotypes

2024-01-10

Abstract excerpt

<title>Abstract</title> <p>Multiple myeloma (MM) is an incurable hematological malignancy with increasing incidence and mortality rates with a worldwide incidence of 160,000 cases per year. The current approved treatments including bortezomib have serious side effects and ultimately develop resistance. Inadequate vitamin D (VD) levels are frequent in MM patients and its supplementation has an antiproliferative ef...

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Literature Corpus work: 54354768-d69c-559b-b825-d405f848a557
DOI: 10.21203/rs.3.rs-3845610/v1

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