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Autophagy-related mechanisms for treatment of multiple myeloma

25 Dec 2023

Abstract excerpt

Multiple myeloma (MM) is a type of hematological cancer that occurs when B cells become malignant. Various drugs such as proteasome inhibitors, immunomodulators, and compounds that cause DNA damage can be used in the treatment of MM. Autophagy, a type 2 cell death mechanism, plays a crucial role in determining the fate of B cells, either promoting their survival or inducing cell death. Therefore, autophagy can...

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PMID: 38239705
DOI: 10.20517/cdr.2023.108

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