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Frequent lncRNA-derived fusions in pediatric neuroblastoma identified by<i>LncFusion</i>: potential biomarker and therapeutic implications

2025-01-21

Abstract excerpt

<h4>ABSTRACT</h4> Despite growing interest in the onco-fusion proteins and long noncoding RNAs (lncRNAs) in cancers, lncRNA-derived fusion transcripts in pediatric cancers remain understudied. To address this gap, we first developed LncFusion , a novel computational pipeline that systematically detects lncRNA-derived fusion transcripts from RNA-seq data. Leveraging our previously published Flnc (for comprehensive...

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Literature Corpus work
1e17c504-269a-50ec-984e-e228f0010b3a
DOI
10.1101/2025.01.16.25320696
Open publication

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Frequent lncRNA-derived fusions in pediatric neuroblastoma identified by<i>LncFusion</i>: potential biomarker and therapeutic implicationsDOI 10.1101/2025.01.16.25320696
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