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Tn-seq of the <i>Candida glabrata</i> reference strain CBS138 reveals epigenetic plasticity, structural variation, and intrinsic mechanisms of resistance to micafungin

2024-05-03

Abstract excerpt

<h4>ABSTRACT</h4> C. glabrata is an opportunistic pathogen that can resist common antifungals and rapidly acquire multidrug resistance. A large amount of genetic variation exists between isolates, which complicates generalizations. Portable Tn-seq methods can efficiently provide genome-wide information on strain differences and genetic mechanisms. Using the Hermes transposon, the CBS138 reference strain and a co...

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Literature Corpus work
fff30c88-cb2d-5a7a-b334-ac7606cfcb7c
DOI
10.1101/2024.05.02.592251
Open publication

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Tn-seq of the <i>Candida glabrata</i> reference strain CBS138 reveals epigenetic plasticity, structural variation, and intrinsic mechanisms of resistance to micafunginDOI 10.1101/2024.05.02.592251
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