Article

Alternative splicing is a developmental switch for hTERT expression

2020-04-03

Abstract excerpt

High telomerase activity is restricted to the blastocyst stage of embryonic development when telomere length is reset, and is characteristic of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). However, the pathways involved in telomerase regulation as a function of pluripotency remain unknown. To explore hTERT transcriptional control, we compare genome-wide interactions (4C-seq) and chromati...

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Literature Corpus work: 950ce8ce-70d4-5a39-82f6-491285749ed7
DOI: 10.1101/2020.04.02.022087

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