Article

Transposable Element-Gene Splicing Modulates the Transcriptional Landscape of Human Pluripotent Stem Cells

2020-07-26

Abstract excerpt

Transposable elements (TEs) occupy nearly 50% of mammalian genomes and are both potential dangers to genome stability and functional genetic elements. TEs can be expressed and exonised as part of a transcript, however, their full contribution to the transcript splicing remains unresolved. Here, guided by long and short read sequencing of RNAs, we show that 26% of coding and 65% of non-coding transcripts of human p...

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Literature Corpus work: 9e692cc2-e460-52dc-a087-e8bb673b1035
DOI: 10.1101/2020.07.26.220608

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