Article

Deconvoluting sex-dependent dendritic cell-monocyte lineages in emphysematous lung tissue with bulk and single-cell RNA sequencing

2022-03-21

Abstract excerpt

<title>Abstract</title> <p>Emphysema is a unique type of chronic obstructive pulmonary disease, and sex may influence susceptibility. After cigarette smoke exposure, murine males and ovariectomized females developed more severe emphysema. Herein, we present divergent bulk and single-cell transcriptomic profiles between male and female murine lungs. Weighted Gene Co-Expression Network Analysis of the bulk lung RNA...

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Literature Corpus work: 95094c14-ad35-5ccf-a475-c3185bfec5ba
DOI: 10.21203/rs.3.rs-1390121/v1

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