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Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations

27 Jun 2024

Abstract excerpt

Abstract Rationale Although many studies have examined gene expression in lung tissue, the gene regulatory processes underlying emphysema are still not well understood. Finding efficient nonimaging screening methods and disease-modifying therapies has been challenging, but knowledge of the transcriptomic features of emphysema may help in this effort. Objectives Our goals were to identify emphysema-associated...

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PMID: 38935868
DOI: 10.1164/rccm.202305-0793oc

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