Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to Smoking

26 Nov 2019

Abstract excerpt

Epidemiological studies have shown that female smokers are at higher risk of chronic obstructive pulmonary disease (COPD). Female patients have worse symptoms and health status and increased risk of exacerbations. We determined the differences in the transcriptome of the airway epithelium between males and females, as well the sex-by-smoking interaction. We processed public gene expression data of human airway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways
Share to Pediatric health and respiratory diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31772224
DOI: 10.1038/s41598-019-54051-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to SmokingPMID 31772224Read ↗

Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to SmokingSemantic proximity Read ↗

Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactionsSemantic proximity Read ↗

Deconvoluting sex-dependent dendritic cell-monocyte lineages in emphysematous lung tissue with bulk and single-cell RNA sequencingSemantic proximity Read ↗

Differential Effect of Active Smoking on Gene Expression in Male and Female SmokersSemantic proximity Read ↗

Cigarette smoke-induced injury induces distinct sex-specific transcriptional signatures in mice tracheal epithelial cellsSemantic proximity Read ↗

Translating the COPD Transcriptome: Insights into Pathogenesis and Tools for Clinical ManagementSemantic proximity Read ↗

Cigarette smoke alters the transcriptome of non-involved lung tissue in lung adenocarcinoma patientsSemantic proximity Read ↗

RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPDSemantic proximity Read ↗

Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Systemic Inflammatory Response to Smoking in Chronic Obstructive Pulmonary Disease: Evidence of a Gender EffectSemantic proximity Read ↗

Meta-analysis of Gene Expression Microarray Datasets in Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPDSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.