Article

On the application of BERT models for nanopore methylation detection

2021-02-10

Abstract excerpt

<h4>Motivation</h4> DNA methylation is a common epigenetic modification, which is widely associated with various biological processes, such as gene expression, aging, and disease. Nanopore sequencing provides a promising methylation detection approach through monitoring abnormal signal shifts for detecting modified bases in target motif regions. Recently, model-based approaches, especially those with deep learnin...

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Literature Corpus work: 94f1c7f5-bbc2-5ff1-b719-af60a4d9e527
DOI: 10.1101/2021.02.08.430070

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