Article

YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution

2023-07-26

Abstract excerpt

Tumor initiation represents the first step in tumorigenesis during which normal progenitor cells undergo cell fate transition to cancer. Capturing this process as it occurs in vivo, however, remains elusive. Here we employ spatiotemporally controlled oncogene activation and tumor suppressor inhibition together with multiomics to unveil the processes underlying oral epithelial progenitor cell reprogramming into tum...

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Identifiers and source

Literature Corpus work: 94eb822f-d4b5-5895-91b6-2e0c04fd23f0
DOI: 10.1101/2023.07.24.550427

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