Article

YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution

2023-10-27

Abstract excerpt

<title>Abstract</title> <p>Tumor initiation represents the first step in tumorigenesis during which normal progenitor cells undergo cell fate transition to cancer. Capturing this process as it occurs <italic>in vivo</italic>, however, remains elusive. Here we employ cell tracing approaches with spatiotemporally controlled oncogene activation and tumor suppressor inhibition to unveil the processes underlying oral...

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Literature Corpus work: b7f7fc38-aeb7-5549-adc3-575479eb18de
DOI: 10.21203/rs.3.rs-3426301/v1

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