Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

1 Aug 2018

Abstract excerpt

The mammary gland consists of cells with gene expression patterns reflecting their cellular origins, function, and spatiotemporal context. However, knowledge of developmental kinetics and mechanisms of lineage specification is lacking. We address this significant knowledge gap by generating a single-cell transcriptome atlas encompassing embryonic, postnatal, and adult mouse mammary development. From these data,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30089273
DOI: 10.1016/j.celrep.2018.07.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland DevelopmentPMID 30089273Read ↗

Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesisSemantic proximity Read ↗

Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epitheliaSemantic proximity Read ↗

Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progressionSemantic proximity Read ↗

Mammary gland development from a single cell ‘omics viewSemantic proximity Read ↗

Hybrid Stem Cell States: Insights Into the Relationship Between Mammary Development and Breast Cancer Using Single-Cell TranscriptomicsSemantic proximity Read ↗

Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expressionSemantic proximity Read ↗

Mammary development in the embryo and adult: new insights into the journey of morphogenesis and commitmentSemantic proximity Read ↗

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.Semantic proximity Read ↗

Dissecting the mammary gland one cell at a timeSemantic proximity Read ↗

Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancerSemantic proximity Read ↗

Characterization of Gene Expression Signatures for the Identification of Cellular Heterogeneity in the Developing Mammary GlandSemantic proximity Read ↗

Dynamic Allelic Expression in Mouse Mammary Gland Across the Adult Developmental CycleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.