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Single‐cell transcriptomic analysis of gingivo‐buccal oral cancer reveals two dominant cellular programs

4 Oct 2023

Abstract excerpt

Abstract Oral squamous cell carcinoma of the gingivo‐buccal region (OSCC‐GB) is the most common cancer among men in India, and is associated with poor prognosis and frequent recurrence. Cellular heterogeneity in OSCC‐GB was investigated by single‐cell RNA sequencing of tumors derived from the oral cavity of 12 OSCC‐GB patients, 3 of whom had concomitant presence of a precancerous lesion (oral submucous fibrosis...

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PMID: 37792582
DOI: 10.1111/cas.15979

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