Article

Pan-cancer prevalence of microsatellite instability and Lynch syndrome in India

2026-06-30

Abstract excerpt

<title>Abstract</title> <p> Lynch syndrome (LS) is underdiagnosed in India, particularly outside colorectal cancer (CRC), because pan-cancer data on microsatellite instability (MSI), mismatch repair deficiency (MMRd), and germline predisposition remain limited. We sequentially recruited 519 patients with CRC and extra-colonic cancers from 17 centres in India between 2019 and 2025, and applied a tumour-first appr...

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Literature Corpus work: 94d1b9b5-d631-5d39-9ac2-f3b5c1b587ba
DOI: 10.21203/rs.3.rs-9894863/v1

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