Article

High Probability of Lynch Syndrome among colorectal cancer patients in Indonesia is associated with higher occurrence of KRAS and PIK3CA mutations

2024-03-04

Abstract excerpt

<h4>Background</h4> In Indonesia, early-onset colorectal cancer (EOCRC) rates are higher in patients <50 years old compared to western populations, possibly due to a higher frequency of Lynch Syndrome (LS) in CRC patients. We aim to examine the association of KRAS and PIK3CA mutation with LS. <h4>Methods</h4> In this cross-sectional study, the PCR-HRM-based test was used for screening of MSI mononucleotide markers...

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Literature Corpus work: 30d6bf35-3e69-55e5-85a7-5d48b35b8dad
DOI: 10.1101/2024.03.03.24303469

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