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Multidomain determinants of perivascular spaces indicate early cerebrovascular vulnerability in individuals at risk of Alzheimer’s disease

2026-03-25

Abstract excerpt

<h4>Background</h4> Perivascular spaces (PVS) are increasingly recognized as MRI-visible markers of cerebrovascular and glymphatic functions. However, the determinants of regional PVS burden in the preclinical stages of Alzheimer’s disease (AD) remain to be elucidated, particularly when considering the impact of sex and core AD biomarkers. <h4>Methods</h4> We studied 1,199 cognitively unimpaired participants fro...

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Literature Corpus work
94b5ca21-ec87-5e3f-85f4-bbc9a2f2f0a1
DOI
10.64898/2026.03.23.26349050
Open publication

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Multidomain determinants of perivascular spaces indicate early cerebrovascular vulnerability in individuals at risk of Alzheimer’s diseaseDOI 10.64898/2026.03.23.26349050
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