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Article

Topography and Determinants of Magnetic Resonance Imaging (MRI)-Visible Perivascular Spaces in a Large Memory Clinic Cohort.

Journal of the American Heart Association - 22 Sept 2017

Shams Sara, Martola Juha, Charidimou Andreas, Larvie Mykol, Granberg Tobias, Shams Mana, Kristoffersen-Wiberg Maria, Wahlund Lars-Olof

Abstract excerpt

BACKGROUND: Magnetic resonance imaging-visible perivascular spaces (PVS) are related to interstitial fluid clearance pathways (including amyloid-β) in the brain and are suggested to be a marker of cerebral small vessel disease. We investigated the role, topography, and possible implications of PVS in cognitive impairment. METHODS AND RESULTS: A total of 1504 patients undergoing memory clinic investigation and an...

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Identifiers

PMID: 28939709
DOI: 10.1161/JAHA.117.006279
PMCID: PMC5634282

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