Article

<i>Klf4</i> -dependent pivotal role of smooth muscle-derived <i>Gli1</i> <sup>+</sup> lineage progenitor cells in lung cancer progression

2025-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite the remarkable efficacy of immune checkpoint inhibitors, only a subset of lung adenocarcinoma (LUAD) patients respond and many eventually progress, underscoring the need to develop novel combination therapies. The interaction between cancer cells and the tumor microenvironment (TME), a complex niche including cells...

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Literature Corpus work: 94a53fac-0cc4-54d9-be31-a19a89941b0f
DOI: 10.1101/2025.05.30.657094

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