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Integration of urine proteomics and renal single-cell genomics identifies an interferon-gamma response gradient in lupus nephritis

2020-03-17

Abstract excerpt

Lupus nephritis, one of the most serious manifestations of systemic lupus erythematosus (SLE), has both a heterogeneous clinical and pathological presentation. For example, proliferative nephritis identifies a more aggressive disease class that requires immunosuppression. However, the current classification system relies on the static appearance of histopathological morphology which does not capture differences in...

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Literature Corpus work
2ecd1e87-6124-5bd7-ae93-f4a1b0956ec4
DOI
10.1101/2020.03.13.20034348
Open publication

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Integration of urine proteomics and renal single-cell genomics identifies an interferon-gamma response gradient in lupus nephritisDOI 10.1101/2020.03.13.20034348
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