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Article

Apolipoprotein L1 Risk Genotypes in Ghanaian Systemic Lupus Erythematosus Patients: A Prospective Cohort Study

2020-10-22

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>Two Apolipoprotein L1 (<italic>APOL1</italic>) risk variants (RV) are enriched in sub-Saharan African populations due to a conferred resistance to <italic>Trypanosoma brucei</italic>. This comes at the cost of progressive renal disease by multiple causes including systemic lupus erythematosus (SLE). In African Americans, <italic>APOL1</italic> high-risk genotypes...

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Literature Corpus work
947fe58c-987f-57ee-8f26-6f3e5455f0f9
DOI
10.21203/rs.3.rs-93715/v1
Open publication

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