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No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

2017-08-25

Abstract excerpt

<h4>Background:</h4> Human African trypanosomiasis (HAT) manifests as an acute form caused by Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei gambiense (Tbg). Previous studies have suggested a host genetic role in infection outcomes, particularly for APOL1 . We have undertaken a candidate gene association studies (CGAS) in a Ugandan Tbr and a Tbg HAT endemic area, to determ...

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Literature Corpus work
807a52d4-b17f-5ab0-ba76-9233ceeace40
DOI
10.1101/180679
Open publication

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No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populationsDOI 10.1101/180679
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