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Article

Apolipoprotein L1 risk genotypes in Ghanaian patients with systemic lupus erythematosus: a prospective cohort study.

Lupus science & medicine - 1 Jan 2021

Blazer Ashira, Dey Ida Dzifa, Nwaukoni Janet, Reynolds Margaret, Ankrah Festus, Algasas Huda, Ahmed Tasneem, Divers Jasmin

Abstract excerpt

OBJECTIVE: Two apolipoprotein L1 (APOL1) risk variants (RV) are enriched in sub-Saharan African populations due to conferred resistance to Trypanosoma brucei. These variants associate with adverse renal outcomes by multiple causes including SLE. Despite emerging reports that SLE is common in Ghana, where APOL1 variant allelic frequencies are high, the regional contribution to SLE outcomes has not been described....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33461980
DOI: 10.1136/lupus-2020-000460
PMCID: PMC7816898

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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