Article

Tissue-specific Enrichment of Lymphoma Risk Loci in Regulatory Elements

2015-04-07

Abstract excerpt

Though numerous polymorphisms have been associated with risk of developing lymphoma, how these variants function to promote tumorigenesis is poorly understood. Here, we report that lymphoma risk SNPs, especially in the non-Hodgkin’s lymphoma subtype chronic lymphocytic leukemia, are significantly enriched for co-localization with epigenetic marks of active gene regulation. These enrichments were seen in a lymphoid...

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Literature Corpus work: 947dc963-b96d-5c3a-a2c5-effa44126db4
DOI: 10.1101/017657

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