Article
Post-GWAS functional characterization of susceptibility variants for chronic lymphocytic leukemia.
PloS one - 1 Jan 2012
Sillé Fenna C M, Thomas Reuben, Smith Martyn T, Conde Lucia, Skibola Christine F
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified several gene variants associated with sporadic chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Many of these CLL/SLL susceptibility loci are located in non-coding or intergenic regions, posing a significant challenge to determine their potential functional relevance. Here, we review the literature of all CLL/SLL GWAS and validation...
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