Article

A natural mutator allele shapes mutation spectrum variation in mice

2021-03-13

Abstract excerpt

<h4>Summary Paragraph</h4> Although germline mutation rates and spectra can vary within and between species, genetic modifiers of these traits have long eluded detection. In this study, we searched for loci that influence germline mutagenesis using a uniquely powerful resource: a panel of recombinant inbred mouse lines known as the B X D , descended from the laboratory mouse strains C57BL/6J ( B ) and DBA/2J (...

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Literature Corpus work: 94391666-8bb3-5f45-8597-6567e8b005ec
DOI: 10.1101/2021.03.12.435196

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