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Article

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations.

Genome biology - 1 Aug 2016

Doran Anthony G, Wong Kim, Flint Jonathan, Adams David J, Hunter Kent W, Keane Thomas M

Abstract excerpt

BACKGROUND: The Mouse Genomes Project is an ongoing collaborative effort to sequence the genomes of the common laboratory mouse strains. In 2011, the initial analysis of sequence variation across 17 strains found 56.7 M unique single nucleotide polymorphisms (SNPs) and 8.8 M indels. We carry out deep sequencing of 13 additional inbred strains (BUB/BnJ, C57BL/10J, C57BR/cdJ, C58/J, DBA/1J, I/LnJ, KK/HiJ, MOLF/EiJ,...

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Identifiers

PMID: 27480531
DOI: 10.1186/s13059-016-1024-y
PMCID: PMC4968449

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Source receipt: pubmed, retrieved 7 Sept 2026.

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