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Article

Sex-dependent gene co-expression in the human body.

Scientific reports - 21 Sept 2021

Hartman Robin J G, Mokry Michal, Pasterkamp Gerard, den Ruijter Hester M

Abstract excerpt

Many pathophysiological mechanisms in human health and disease are dependent on sex. Systems biology approaches are successfully used to decipher human disease etiology, yet the effect of sex on gene network biology is mostly unknown. To address this, we used RNA-sequencing data of over 700 individuals spanning 24 tissues from the Genotype-Tissue Expression project to generate a whole-body gene co-expression map...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34548535
DOI: 10.1038/s41598-021-98059-9
PMCID: PMC8455523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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