Article
Understanding the sexome: measuring and reporting sex differences in gene systems.
Endocrinology - 1 Jun 2012
Arnold Arthur P, Lusis Aldons J
Abstract excerpt
The current male bias in biomedical research should be eliminated. The large sex differences in incidence and progression of diseases mean that sex-biased factors are an untapped source of factors that protect from disease. Greater understanding will come from intensified study of the "sexome," which is the sum of sex-biased effects on gene networks and cell systems. The global search for sites and mechanisms of...
Topics
- Female
- Gene Regulatory Networks
- Genetic Predisposition to Disease
- Humans
- Male
- Models, Genetic
- Sex Factors
- Transcriptome