Article
Sexual dimorphism in gene expression and regulatory networks across human tissues
2016-10-20
Abstract excerpt
<h4>Summary</h4> Sexual dimorphism manifests in many diseases and may drive sex-specific therapeutic responses. To understand the molecular basis of sexual dimorphism, we conducted a comprehensive assessment of gene expression and regulatory network modeling in 31 tissues using 8716 human transcriptomes from GTEx. We observed sexually dimorphic patterns of gene expression involving as many as 60% of autosomal gen...
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Identifiers and source
- Literature Corpus work
- 2ef03830-8a40-58b3-bdc0-121510315dc7
- DOI
- 10.1101/082289