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Molecular landscapes of human hematopoietic stem cells in health and leukemia

11 Dec 2015

Abstract excerpt

Blood cells are organized as a hierarchy with hematopoietic stem cells (HSCs) at the root. The advent of genomic technologies has opened the way for global characterization of the molecular landscape of HSCs and their progeny, both in mouse and human models, at the genetic, transcriptomic, epigenetic, and proteomics levels. Here, we outline our current understanding of the molecular programs that govern human...

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Share to Acute Myeloid Leukemia Research
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PMID: 26663266
DOI: 10.1111/nyas.12981

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